How Does Memory Of Personal Interactions Decline With Age?

news 30 september featured
Spread the love

Brain News

Researchers at the University of Maryland School of Medicine (UMSOM) provided insights into the mechanisms behind the age-related decline in any memory of personal interactions. The study is published in the journal Aging Cell.

The Study

In order to understand the link between social interactions, aging, and memory, the research team sought to determine the role played by an enzyme, known as PDE11A, in the brain area containing memories of social interactions. They studied mouse “social interaction”.

They surveyed the subject mice’s willingness to try new food based on social associative memory. This social associative memory was formed by smelling food on another mouse’s breath or the smell of the other mouse’s pheromones.

The Findings

The results provided interesting insights into how and why memories decline with age. It revealed that the levels of the PDE11A enzyme increase with age, especially in the hippocampus which stores any memory of personal interactions or learning.

This triggers and accelerates age-related memory loss and cognitive decline associated with social interactions. It was also found that genetically deleting the PDE11A gene helps abate the loss of social associative memory.

Speaking on the possibility of incorporating gene removal therapy in the treatment of memory disorders, one of the lead researchers, Dr. Kelly, elaborated: “PDE11 is involved in more things than just memory. So, if we are to develop a therapy to help with cognitive decline, we [should figure out a way] to target the bad form of PDE11A specifically, in order to not interfere with the normal, healthy function of the enzyme.

To Know More You May Refer To

Pilarzyk, K., Porcher, L., Capell, W. R., Burbano, S. D., Davis, J., Fisher, J. L., Gorny, N., Petrolle, S., & Kelly, M. P. (2022). Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories. Aging cell, e13687. Advance online publication. https://doi.org/10.1111/acel.13687


Spread the love
  • ADHD Linked To Dementia Across Generations, New Study Claims

    Researchers found that parents and grandparents of individuals with ADHD…

  • Sibling Fights Linked To Poor Mental Health In Children And Adolescents, Says New Study

    Researchers at University of New Hampshire found that sibling aggression…

  • Teens Playing School Sports Have Better Mental Health: Study

    New research found adolescents playing team sports in grades 8…

  • Bird Watching Near Home Improves Mental Health, New Study Finds

    New study found that being able to see more birds,…

  • Mental Health Services For Teenagers Lower Depression In Adolescence: Study

    Researchers at the University of Cambridge found that teenagers with…

  • Sunshine Boosts Mental Health More Than Any Other Weather Variable: Study

    The time between sunrise and sunset matters most when it…

  • Your Driving Habits Can Reveal Early Signs Of Alzheimer’s, Scientists Say

    Studies have found that people with symptomatic Alzheimer disease (AD)…

  • Mental Health Effects By Traffic Police Harassment

    Mental Health Effects By Traffic Police Harassment

    Traffic police harassment is a very common occurrence that numerous…

  • Narcissism Changes Throughout Life, New Study Finds

    New research published in Psychology and Aging, found that narcissism…

  • Excessive Posting Of Selfies On Social Media Can Make You A Narcissist, Researchers Say

    Excessive Posting Of Selfies On Social Media Can Make You A Narcissist, Researchers Say

    Excessive use of social media, in particular, the posting of…

  • Not All Psychopaths Are Criminals – Some Are Successful Instead, New Study Finds

    People view all psychopaths as violent. The study provides insights…

  • PTSD Increases Ovarian Cancer Risk, Study Claims

    Researchers found that women who experienced six or more symptoms…

  • Scientists Find A Network Of Neurons That Influence Eating Behavior

    University of Arizona researchers have identified a network of neurons…

  • A Racing Heart Can Alter Your Decision-Making Ability, Scientists Find

    Body-state monitoring neurons can hijack the decision-making process, according to…

  • Seasonal Variation In Daylight Influences Brain Function, New Study Confirms

    We experience more negative emotions in winters than in summer.…

  • Distrust Of The Past Can Fuel Obsessive-Compulsive Symptoms, Study Says

    Distrust of past experiences can lead to increased uncertainty, indecisiveness,…

  • Meditation Helps You Make Fewer Mistakes, Scientists Find In New Study

    Researchers from Michigan State University found that If you are…

  • Thinking Leisure Is A Waste Hampers Your Mental Health, Study Suggests

    If people start to believe that leisure is wasteful and…

  • Short Naps During Day Don’t Relieve Sleep Deprivation, Study Says

    Short naps don’t mitigate the potentially dangerous cognitive effects of…

  • Survivors Of Trauma Experience Persistent Grief Years Later, Study Finds

    New study finds that people who survive a trauma that…

  • Exposure To Antibiotics In Early Life Can Affect Brain Development

    Researchers at Rutgers University found exposure to antibiotics in early…

  • New Study Claims Only 10% Of Kids With ADHD Outgrow It As Adults

    Contrary to a popular notion, most children with attention deficit…

  • Scientists Find Histamine As A Potential Key Player In Depression

    New study finds that body inflammation and release of the…

  • Insomnia In Children Increases The Risk Of Mood, Anxiety Disorders In Adulthood, Study Claims

    Childhood insomnia symptoms that persist into adulthood are strong determinants…

  • Addiction To Sun Is In Your Genes, Research Says

    People who love basking in sun have genes involved in…

  • Scientists Confirm Dual Beneficial Effect Of Physical Activity In Depression

    New research reveals that physical activity not only reduces depressive…